This article provides an in-depth look at the Portuguese Flexo Printer Slotter Die Cutter machine manufacturing sector, focusing on local companies designing and assembling advanced packaging machinery. It covers core machine functions, key Portuguese manufacturers, technological innovations, and criteria to select suitable machines for corrugated carton production. The emphasis is on customization, environmental compliance, and after-sales support, ensuring Portugal’s packaging producers obtain efficient, high-quality, and sustainable machinery solutions.