This article reviews the leading corrugated box slotting machine manufacturers and suppliers targeting the American market, including stalwarts like Sun Automation Group and Bobst and innovative players like Keshenglong & Shinko and Aopack. It explains operational principles, compares industry leaders, and guides readers on selecting the right machines based on production scale, customization needs, and technological features. The article also addresses frequently asked questions and highlights trends like Industry 4.0 integration and OEM collaborations. This comprehensive overview aids packaging professionals in making well-informed decisions that enhance manufacturing efficiency and product quality.